Fortunately, as studies continue to demonstrate the importance of DHA for both adults and children, supplements and foods that provide docosahexaenoic acid are becoming more widely available. This means it’s now relatively easy to include sources of DHA in your diet regularly, especially the richest food sources of omega-3s like wild-caught fish, such as salmon, sardines and herring.

Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. We avoid using tertiary references. We link primary sources — including studies, scientific references, and statistics — within each article and also list them in the resources section at the bottom of our articles. You can learn more about how we ensure our content is accurate and current by reading our editorial policy. Docosahexaenoic acid taken alone or used in combination with chemotherapy can exert anticancer activity by causing apoptosis in human cancer cells. One study out of Italy reported that supplementation with two grams per day of fish oil for the first nine weeks of chemotherapy contributed to delay in tumor progression in colorectal patients. A Voss; M Reinhart; S Sankarappa; H Sprecher (October 1991). "The metabolism of 7,10,13,16,19-docosapentaenoic acid to 4,7,10,13,16,19-docosahexaenoic acid in rat liver is independent of a 4-desaturase". The Journal of Biological Chemistry. 266 (30): 19995–20000. doi: 10.1016/S0021-9258(18)54882-1. PMID 1834642 . Retrieved January 2, 2011. Fish oil containing DHA has been shown to help reduce triglycerides in the blood and decrease thrombosis, plus help prevent cardiac arrhythmias. DHA may also protect against endothelial dysfunction, which is a catalyst to cardiovascular disease. The American Heart Association recommends consuming fish, particularly fatty fish, at least two times per week to support overall heart health. 7. Improves Acne Hindari penggunaan alkohol saat menggunakan suplemen ini, sebab alkohol dapat meningkatkan kadar trigliserida dan berpotensi membuat kondisi Anda semakin buruk.

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Apabila Anda melupakan satu dosis DHA, minum sesegera mungkin dosis yang terlupa. Namun bila saat Anda hendak mengonsumsi dosis yang terlupa ternyata sudah mendekati waktu dosis berikutnya, lewati dosis yang terlupakan dan kembali ke jadwal dosis yang biasa. Suplemen ini termasuk ke dalam golongan obat bebas yang artinya Anda bisa membelinya di apotek secara bebas baik tanpa maupun dengan resep dari dokter. Bagaimana saya menggunakan docosahexaenoic acid (DHA)? a b c d Burdge, G. C.; Jones, A. E.; Wootton, S. A. (2002). "Eicosapentaenoic and docosapentaenoic acids are the principal products of α-linolenic acid metabolism in young men". British Journal of Nutrition. 88 (4): 355–363. doi: 10.1079/BJN2002662. PMID 12323085. Denomme J, Stark KD, Holub BJ (2005). "Directly quantitated dietary (n-3) fatty acid intakes of pregnant Canadian women are lower than current dietary recommendations". The Journal of Nutrition. 135 (2): 206–11. doi: 10.1093/jn/135.2.206. PMID 15671214.

Be wary of products stated to exceed the standard maximum allowances of harmful heavy metals, toxins, and oxidation set by one or more of these organizations. In terms of dietary consumption, pregnant people should aim to eat a minimum of two servings of low mercury shellfish or fish per week before and during pregnancy and while nursing. One serving of fish contains 9–12 ounces (oz). Experts now tell us that from a nutritional standpoint, older individuals who tend to have a higher than optimal omega-6/omega-3 ratio should make an effort to increase DHA consumption (from food and/or fish oils) to help protect their vision. 4. Treats Rheumatoid Arthritis Symptoms Liao Y, Xie B, Zhang H, et al. Efficacy of omega-3 PUFAs in depression: A meta-analysis. Transl Psychiatry. 2019;9(1):190. doi:10.1038/s41398-019-0515-5By comparison with early humans, the gross expansion of grey matter and enlarged cerebral cortex coincides with increased intelligence in modern humans. Perhaps the most widely held theory of evolution explains the growth of human intelligence as due to an interaction between tool making, language development and brain expansion. However, Cunnane and Crawford [ 7] argue that brain expansion due to the discovery of a convenient source of high-quality dietary nutrients is likely to have preceded both the expansion of the grey matter and the development of language and tools making. Considering how vital the healthy fat docosahexaenoic acid (DHA) is, it’s no wonder more people are taking DHA supplements to support their nervous system, heart and brain than ever before. The research was performed in mice, in which half were given a DHA-rich fish oil supplement for five weeks. As a result, the mice who were on the DHA supplement showed enhanced antibody production and cell activation. Docosahexaenoic acid ( DHA) is an omega-3 fatty acid that is a primary structural component of the human brain, cerebral cortex, skin, and retina. In physiological literature, it is given the name 22:6(n-3). It can be synthesized from alpha-linolenic acid or obtained directly from maternal milk (breast milk), fatty fish, fish oil, or algae oil. [1] DHA is a major fatty acid in brain phospholipids and the retina. Research into the potential role or benefit of DHA in various pathologies is ongoing, [8] with significant focus on its mechanism in Alzheimer's disease [9] and cardiovascular disease. [10] Central nervous system constituent [ edit ]

Brains from mammals taken as food are also a good direct source. Beef brain, for example, contains approximately 855mg of DHA per 100 grams in a serving. [32] While DHA may be the primary fatty acid found in certain specialized tissues, these tissues, aside from the brain, are typically small in size, such as the seminiferous tubules and the retina. As a result, animal-based foods, excluding the brain, generally offer minimal amounts of preformed DHA. [33] Discovery of algae-based DHA [ edit ] Many trustworthy organizations set standards that assess the quality and purity of fish oil products, such as the following: If you’ve ever tried to buy fish oil or algae supplements before, you’re probably aware of just how many options there now are to choose from. In addition to eating oily fish, DHA supplements are recommended for most people — whether you’re pregnant, looking to give docosahexaenoic acid to your child or you’re an adult who wants to maintain healthy cognitive function as you age. A systematic review found that DHA had no significant benefits in improving visual field in individuals with retinitis pigmentosa. [29] Animal research shows effect of oral intake of deuterium-reinforced DHA (D-DHA) for prevention of macular degeneration. [30] Nutrition [ edit ] Algae-based DHA supplementsFor prevention of cardiovascular disease, 300–600 milligrams of DHA and EPA per day is recommended.

Simmer K. Fish-oil supplementation: the controversy continues. Am J Clin Nutr. 2016;103(1):1-2. doi:10.3945/ajcn.115.126607 Crawford, M; etal. (2000). "Evidence for the unique function of docosahexaenoic acid (DHA) during the evolution of the modern hominid brain". Lipids. 34 (S1): S39–S47. doi: 10.1007/BF02562227. PMID 10419087. S2CID 4060454.Blood triglycerides. Long-chain omega-3 fatty acids may reduce blood triglycerides by up to 30% ( 65, 66, 67, 68, 69). One study followed 4,162 American children for 20 years, documenting intake of omega-3 fatty acids as well as those who developed asthma. As a result, those with the highest intake of omega-3 fatty acids were 54 percent less likely to have asthma. Cederholm T, Salem N Jr, Palmblad J (2013). "ω-3 fatty acids in the prevention of cognitive decline in humans". Adv Nutr. 4 (6): 672–6. doi: 10.3945/an.113.004556. PMC 3823515. PMID 24228198. a b Albert, Benjamin B (21 January 2015). "Fish oil supplements in New Zealand are highly oxidised and do not meet label content of n-3 PUFA release". Scientific Reports. 5: 7928. doi: 10.1038/srep07928. PMC 4300506. PMID 25604397. DHA is the most abundant omega-3 in your brain and plays a critical role in its development and function.