Bee Health Propolis Lozenges 114 g Pack of 2

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Afkhamizadeh M, Aboutorabi R, Ravari H, et al. Topical propolis improves wound healing in patients with diabetic foot ulcer: a randomized controlled trial. Nat Prod Res. 2018;32(17):2096-2099. View abstract. Cohen, H. A., Varsano, I., Kahan, E., Sarrell, E. M., and Uziel, Y. Effectiveness of an herbal preparation containing echinacea, propolis, and vitamin C in preventing respiratory tract infections in children: a randomized, double-blind, placebo-controlled, multicenter study. Arch.Pediatr.Adolesc.Med. 2004;158(3):217-221. View abstract. To the best of our knowledge, this is the first report published on the antioxidant activity of Indian propolis extract and its chemical constituent's pinocembrin and galangin. In all the antioxidant assay systems, aqueous extract of propolis (AEP) showed higher activity compared to the ethanolic extract of propolis (EEP). This may be due to its higher polyphenols content. So, AEP can be a good substitute of ethanol extract. Moreover, it can be used in prevention of various free radical related diseases. Galangin also showed comparable activity with that of AEP and EEP and highest activity than pinocembrin. This is due to structural differences between these two compounds. Further research is underway to analyze the constituents of AEP and their antioxidant activity [ 18].

Amoros M, Lurton E, Boustie J, et al. Comparison of the anti-herpes simplex virus activities of propolis and 3-methyl-but-2-enyl caffeate. J Nat Prod 1994;57:644-7. View abstract. Soleimani D, Miryan M, Hadi V, et al. Effect of propolis supplementation on athletic performance, body composition, inflammation, and oxidative stress following intense exercise: a triple-blind randomized clinical trial. Food Sci Nutr 2021;9(7):3631-40. View abstract. B-complex vitamins are critical to keeping your body functioning well. A deficiency in vitamin B6, for example, can lead to anemia — causing symptoms like confusion and depression. Adding propolis to your diet can help you reduce your risk of a B-complex deficiency and associated anemia. Amounts and DosageHoney and propolis provide beneficial effect on human health. Since ancient times propolis has been extensively employed by man, especially in folk medicine to treat several maladies. Egyptians used bee glue to embalm their cadavers as they well knew about its putrefactive properties. Incas employed propolis as an antipyretic agent. Greek and Roman physicians used it as mouth disinfectant and as an antiseptic and healing product in wound treatment, prescribed for topical therapy of cutaneous and mucosal wounds [ 2]. Propolis was listed as an official drug in the London pharmacopoeias of the 17th century. Due to its antibacterial activity, in Europe propolis became very popular between the 17th and 20th centuries. In Italy bee glue was used as a violin varnish [ 3] by Stradivari. In the end of the 19th century, propolis was widely used due to its healing properties and in the Second World War it was employed in several Soviet clinics for tuberculosis treatment, due to the observed decline of lung problems and appetite recovery. In the Balkan states propolis was applied to treat wounds and burns, sore throat, and stomach ulcer [ 4]. The first scientific work with propolis was published in 1908 including its chemical properties and composition which was further indexed to chemical abstract [ 5].

Koo HJ, Lee KR, Kim HS, Lee BM. Detoxification effects of aloe polysaccharide and propolis on the urinary excretion of metabolites in smokers. Food Chem Toxicol. 2019;130:99-108. View abstract. Murray, M. C., Worthington, H. V., and Blinkhorn, A. S. A study to investigate the effect of a propolis-containing mouthrinse on the inhibition of de novo plaque formation. J Clin Periodontol. 1997;24(11):796-798. View abstract. Fukuda T, Fukui M, Tanaka M, et al. Effect of Brazilian green propolis in patients with type 2 diabetes: a double-blind randomized placebo-controlled study. Biomed Rep 2015;3(3):355-60. View abstract. Pina GM, Lia EN, Berretta AA, et al. Efficacy of Propolis on the Denture Stomatitis Treatment in Older Adults: A Multicentric Randomized Trial. Evid Based Complement Alternat Med. 2017;2017:8971746. View abstract. da Rosa C, Bueno IL, Quaresma ACM, Longato GB. Healing potential of propolis in skin wounds evidenced by clinical studies. Pharmaceuticals. 2022;15(9):1143. doi:10.3390/ph15091143Bosio, K., Avanzini, C., D'Avolio, A., and et al. In vitro activity of propolis against Streptococcus pyogenes. Lett Appl.Microbiol. 2000;31(2):174-177. View abstract. Afsharpour F, Javadi M, Hashemipour S, Koushan Y, Haghighian HK. Propolis supplementation improves glycemic and antioxidant status in patients with type 2 diabetes: a randomized, double-blind, placebo-controlled study. Complement Ther Med 2019;43:283-8. View abstract. Hoheisel O. The effects of Herstat (3% propolis ointment ACF ) application in cold sores: a double-blind placebo-controlled clinical trial. Journal of Clinical Research 2001;4:65-75. Korkina, L. G. Phenylpropanoids as naturally occurring antioxidants: from plant defense to human health. Cell Mol.Biol (Noisy.-le-grand) 2007;53(1):15-25. View abstract. Xuan H, Li Z, Yan H, et al. Antitumor activity of Chinese propolis in human breast cancer mcf-7 and mda-mb-231 cells. Evidence-Based Complementary and Alternative Medicine. 2014;2014:1-11. doi:10.1155/2014/280120

Matsumoto Y, Takahashi K, Sugioka Y, et al. Double-blinded randomized controlled trial to reveal the effects of Brazilian propolis intake on rheumatoid arthritis disease activity index; BeeDAI. PLoS One 2021;16(5):e0252357. View abstract. Many analytical methods have been used for separation and identification of propolis constituents and the substances identified belong to the following groups of chemically similar compounds: polyphenols; benzoic acids and derivatives; cinnamic alcohol and cinnamic acid and its derivatives; sesquiterpene and triterpene hydrocarbons; benzaldehyde derivatives; other acids and respective derivatives; alcohols, ketones, and heteroaromatic compounds; terpene and sesquiterpene alcohols and their derivatives; aliphatic hydrocarbons; minerals; sterols and steroid hydrocarbons; sugars and amino acids [ 13]. As it may be expected, volatile compounds (produced by the source plants) are present in low amounts [ 10]. Sugars are thought to be introduced accidentally during the elaboration of propolis and/or passage of bees over the resin. Some compounds are common in all propolis samples and determine its characteristics properties.

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Cai T, Tamanini I, Cocci A, et al. Xyloglucan, hibiscus and propolis to reduce symptoms and antibiotics use in recurrent UTIs: a prospective study. Future Microbiol. 2019;14:1013-1021. View abstract.

Volpert, R. and Elstner, E. F. Interactions of different extracts of propolis with leukocytes and leukocytic enzymes. Arzneimittelforschung 1996;46(1):47-51. View abstract.Grange, J. M. and Davey, R. W. Antibacterial properties of propolis (bee glue). J R.Soc Med 1990;83(3):159-160. View abstract. S. cricetus, S. faecalis, S. Pneumonia, S. pyogenes, S. β-haemolyticus, S. mutans, S. sobrinus, and S. viridians) Usually, cold agglutinin anemia affects people that are older. The disease is diagnosed by a physical exam, and the Coomb's test. If the red blood cells destruction seem to be slowing on its own, treatment therapies, usually, isn’t needed. Other treatments for cold agglutinin anemia are corticosteroids, and splenectomy (removal of the spleen). There is no cure for cold agglutinin disease. Braakhuis A. Evidence on the health benefits of supplemental propolis. Nutrients. 2019;11(11):2705. doi: 10.3390/nu11112705